Anti Human IgA (hIgA) Monoclonal Antibody
Clone HI491 Catalog#: A50491
Description: Type A immunoglobulin (IgA) plays an important role in mucosal immunity. On the membrane, the content of IgA is more than that of other types of antibodies. IgA usually exists in monomer and dimer forms, and can be divided into two sub-groups, IgA1 and IgA2, both of which are highly glycosylated immunoglobulin molecules. Serum IgA1 accounts for about 80% of the total IgA. According to the secretion location of IgA, it can also be divided into serum IgA and secretory IgA. IgA is closely related to human genetics, anti-infection immunity, immune-related diseases, and drugs related to related diseases. Therefore, specific monoclonal antibodies against IgA can be used as diagnostic reagents.
Isotype: |
Mouse IgG |
Species reactivity: |
Mouse |
Production: |
Tissue culture |
Purification: |
Protein A/G |
Applications: |
ELISA, IFA, FACS, WB, ICA |
Immunogen: |
Purified natural IgA in human plasma |
Storage: |
Store at +4°C short term (1-2 weeks). Store at -20°C long term. |
Formulation: |
PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug. |
Clonality: |
Monoclonal |
Reference:
1.Rollino C, Vischini G, et al.(2016).IgA nephropathy and infections.JNephrol.Aug;29(4):463-8.
2.Singh K, Chang C, et al. (2014). IgA deficiency and autoimmunity. Autoimmun Rev.Feb;13(2):163-77.
3.de Sousa-Pereira P,WoofJM.(2019)gA: Structure, Function,andDevelopability.Antibodies (Basel).Dec 5:8(4):57.
Intended for research use only. Not for human, therapeutic, or diagnostic applications.
The buyer cannot sell or otherwise transfer this product for Commercial Purposes without written approval of Humimmu LLC.
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