Anti Human Heparin-binding Protein (hHBP) Monoclonal Antibody
Clone HI487 Catalog#: A50487
Description: Heparin-Binding Protein (HBP) is a protein secreted by mature neutrophils, and its level increases when there is bacterial infection or acute respiratory distress syndrome (ARDS) or acute lung injury (ALI) and respiratory failure. Non-bacterial infections do not increase HBP levels. HBP is one of the earliest markers to increase in bacterial infections, and can be detected in plasma within 1 hour after local or mild bacterial infections, which is an advantage over procalcitonin (PCT). The level of HBP can also be used to identify various types of surgical post-infections.
Isotype: |
Mouse IgG |
Species reactivity: |
Mouse |
Production: |
Tissue culture |
Purification: |
Protein A/G |
Applications: |
ELISA, IFA, FACS, WB, ICA |
Immunogen: |
293T express recombinant hHBP protein |
Storage: |
Store at +4°C short term (1-2 weeks). Store at -20°C long term. |
Formulation: |
PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug. |
Clonality: |
Monoclonal |
Reference:
- Yang Y,Liu G,et al.(2019).A Promising Candidate: Heparin-BindingProtein Steps onto the Stage of Sepsis Prediction, JImmunol Res. Dec16;2019:7515346.
- Fisher J, Linder A.(2017). Heparin-binding protein: a key player in thepathophysiology of organ dysfunction in sepsis.J Intern Med. Jun;281(6):562574.
- Johansson J, Brattstrm O, et al.(2013). Heparin-binding protein (HBP): anearly marker of respiratory failure after trauma? Acta Anaesthesiol Scand.May;57(5):580-6.
Intended for research use only. Not for human, therapeutic, or diagnostic applications.
The buyer cannot sell or otherwise transfer this product for Commercial Purposes without written approval of Humimmu LLC.
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