Anti Human IgM (hIgM) Monoclonal Antibody
Clone HI492 Catalog#: A50492
Description: M-type immunoglobulin (IgM) is a type of animal globulin. Unlike other types of immunoglobulins such as IgG and IgA, IgM is the largest molecular weight and the first type of immunoglobulin molecules produced by the body after encountering the immune antigen/antigen for the first time. The spleen and plasma cells in the human body and most mammals are the main places to produce specific IgM. Mature gM is a pentamer with a heavy chain u chain of about 580aa. IgM is the earliest immunoglobulin molecule produced during embryonic development and also the earliest produced during microbial infection. Therefore, specific monoclonal antibodies against IgM can be used as a useful tool for specific diagnosis of infectious diseases.
Isotype: |
Mouse IgG |
Species reactivity: |
Mouse |
Production: |
Tissue culture |
Purification: |
Protein A/G |
Applications: |
ELISA, IFA, FACS, WB, ICA |
Immunogen: |
Purified natural IgM in human plasma |
Storage: |
Store at +4°C short term (1-2 weeks). Store at -20°C long term. |
Formulation: |
PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug. |
Clonality: |
Monoclonal |
Reference:
- Justiz Vaillant AA, Jamal Z, Ramphul K.(2021).Immunoglobulin. Oct 12In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021Jan -PMID:30035936
- Wei H, Wang JY.(2021). Role of Polymeric Immunoglobulin Receptor inIgA and IgM Transcytosis. Int J Mol Sci. Feb 25;22(5):2284.
Intended for research use only. Not for human, therapeutic, or diagnostic applications.
The buyer cannot sell or otherwise transfer this product for Commercial Purposes without written approval of Humimmu LLC.
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