Anti Human Metapneumovirus NP (hMPV-NP) Monoclonal Antibody
Anti Human Metapneumovirus NP (hMPV-NP) Monoclonal Antibody
Description: Human Metapneumovirus (hMPV) belongs to the Paramyxoviridae family and has a single-stranded negative-sense RNA genome, similar to avian metapneumovirus C group. The virus was first isolated in the Netherlands in 2001. Epidemiological studies have shown that hMPV is the second most common cause of lower respiratory tract infections in children after RSV, accounting for approximately 5%-40% of hospitalized or outpatient respiratory infections in children. Based on genetic sequences, current hMPV strains can be classified into four branches: A1, A2, B1B2. F and G proteins are the main surface glycoproteins of hMPV viral particles, while nucleoprotein NP is the structural protein with high content inside the viral particle. Monoclonal antibodies specifically recognizing hMPV nucleoprotein NP can be used for scientific research and clinical diagnosis applications.
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Isotype: |
Mouse IgG |
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Species reactivity: |
Mouse |
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Production: |
Tissue culture |
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Purification: |
Protein A/G |
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Applications: |
ELISA, WB, IFA, IHC, CLIA, LFA, IP |
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Immunogen: |
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Storage: |
Store at +4°C short term (1-2 weeks). Store at -20°C long term. |
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Formulation: |
PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug. |
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Clonality: |
Monoclonal |
References
1.l.van den Hoogen, Bernadette G.; Jong, Jan C. de; Groen, Jan; Kuiken, Thijs:Groot, Ronald de: Fouchier, Ron A.et al.(2001) A newly discovered human pneumovirus isolated from young children with respiratory tract disease. Nature Medicine.7(6):719-724.
2.Seo, Sachiko: Gooley, Ted A.et al.(2016)Human Metapneumovirus Infections Following Hematopoietic Cell Transplantation: Factors Associated With Disease Progression, Clinical Infectious Diseases.63 (2): 178-185.
3.Leung, Jessica; Esper, Frank; et al.(2005). Sero epidemiology of Human Metapneumovirus (hMPV) on the Basis of a Novel Enzyme-Linked Immunosorbent Assay Utilizing hMPV Fusion Protein Expressed in Recombinant Vesicular Stomatitis Virus. Journal of Clinical Microbiology. 43(3): 1213-1219.
Intended for research use only. Not for human, therapeutic, or diagnostic applications.
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