Anti Streptococcus Anginosus TMPC (S.anginosus-TMPC) Monoclonal Antibody
Anti Streptococcus Anginosus TMPC (S.anginosus-TMPC) Monoclonal Antibody
Clone HI573 Catalog#: A50573
Description: Streptococcus Anginosus TMPC protein, also known as the Tooth-Associated Protein C, is a key virulence factor of this bacterium, which is commonly found in the human oral cavity and is associated with the development of dental caries. TMPC is a glycoprotein that is secreted by Streptococcus Anginosus and is involved in several important processes related to the pathogenesis of dental caries. One of the main functions of TMPC is to bind to collagen, which is a major component of the extracellular matrix in the tooth's outer layers. This binding allows Streptococcus Anginosus to adhere to the tooth surface, forming a biofilm that is more resistant to clearance by saliva and other oral fluids. The biofilm also provides a protective environment for the bacteria, allowing them to thrive and produce acid, which is a major factor in the demineralization of tooth enamel. TMPC has also been shown to have a role in the regulation of the expression of other virulence factors in Streptococcus Anginosus, such as glucan-binding protein B (GBPB) and glucan-binding protein D (GBPD). These proteins are involved in the formation of glucan, a polymer that helps to cement the bacteria to the tooth surface and protects them from the host's immune system.
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Isotype: |
Mouse IgG |
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Species reactivity: |
Mouse |
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Production: |
Tissue culture |
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Purification: |
Protein A/G |
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Applications: |
ELISA, WB, IFA, IHC, CLIA, LFA, IP |
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Immunogen: |
Recombinant S. anginosus/TMPC Antigen |
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Storage: |
Store at +4°C short term (1-2 weeks). Store at -20°C long term. |
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Formulation: |
PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug. |
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Clonality: |
Monoclonal |
Intended for research use only. Not for human, therapeutic, or diagnostic applications.
The buyer cannot sell or otherwise transfer this product for Commercial Purposes without written approval of Humimmu LLC.
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