Anti-Human CD3xClaudin18.2 Bispecific Antibody
Anti-Human CD3xClaudin18.2 Bispecific Antibody
Clone: Grebio Catalog#: MJ0024
Description:
CD3 (cluster of differentiation 3) is a protein complex and T cell co-receptor that is involved in activating both the cytotoxic T cell and T helper cells. The claudin18.2 (CLDN18.2) protein is a member of the tight junction protein family. CLDN18.2 is a highly selective biomarker with limited expression in normal tissues and often abnormal expression during the occurrence and development of various primary malignant tumors.
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Reactivities: |
Human |
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Target: |
CD3xClaudin18.2 |
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Clone: |
Grebio |
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Isotype: |
ScFv-ScFc |
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Alternative Name: |
AMG 910,AMG-910,AMG910;CD3e, CD3 epsilon;SFTPJ, "surfactant associated protein J") isoform 2, extracellular domain 1 (EC1) |
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Recommend Isotype Controls: |
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Recommend Controls CatNo.: |
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Recommended Dilution Buffer: |
ABDB-1002 or PBS, pH 7.4,Contains no stabilizers or preservatives. |
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Immunogen: |
N/A |
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Formulation: |
PBS, pH 7.4,Contains no stabilizers or preservatives |
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Endotoxin: |
<1EU/mg ,Determined by LAL gel clotting assay |
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Purity: |
>95% Determined by SDS-PAGE |
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Sterility: |
0.2 μM filtered |
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Expression System: |
CHO |
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Purification: |
Protein A |
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Storage: |
2 weeks, 2-8°C under sterile conditions after reconstitution. Avoid repeated freeze-thaw. -80°C for a long-term storage. |
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Protocol Information: |
Since applications vary, each investigator should use the application references as a guide to help estimate the appropriate dose or concentration. The dose or concentration can be further optimized experimentally in a dose response or titration experiment. |
Intended for research use only. Not for human, therapeutic, or diagnostic applications.
The buyer cannot sell or otherwise transfer this product for Commercial Purposes without written approval of Humimmu LLC.
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