Anti IL-33 antibody

$699.00
In stock
Catalog
A20006
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Anti IL-33 antibody

Clone HI06 Catalog#: A20006

  

Description: Anti IL-33 monoclonal antibody reacts with human IL-33. Interleukin 33 (IL-33), also known as DVS27 or NF-HEV (Nuclear Factor from High Endothelial enules), is a proinflammatory protein and a chromatin-associated cytokine of the IL-1 family with high sequence and structural similarity to IL-1 and IL-18. IL-33 protein is expressed highly and rather selectively by high endothelial venule endothelial cells (HEVECs) in human tonsils, Peyers's patches, and lymph nodes. IL-33 protein has transcriptional regulatory properties, and the researchers suggested that IL-33 is a dual-function protein that might act both as a cytokine and as an intracellular nuclear factor. As a type 2 cytokines, IL-33 protein also plays a pivotal role in helminthic infection and allergic disorders.

 

 

Isotype:

Mouse IgG1

Species reactivity:

Mouse

Production:

Tissue culture

Purification:

Protein A/G

Applications:

ELISA, IFA, WB,etc.

Immunogen: 

Human IL-33

Storage: 

Store at +4°C short term (1-2 weeks). Store at -20°C long term.

Formulation:

PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug.

Clonality:

Monoclonal

 

References

1. Iikura M, et al. (2007). IL-33 can promote survival, adhesion and cytokine production in human mast cells. Lab Invest. 87(10): 971-8.

2. Lamkanfi M, et al. (2009). IL-33 raises alarm. Immunity. 31(1): 5-7.

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