Anti IGFBP4 antibody

$699.00
In stock
Catalog
A20009
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Anti IGFBP4 antibody

Clone HI09  Catalog#: A20009

Description: Anti IGFBP4 monoclonal antibody reacts with human Insulin-like growth factor-binding protein 4 (IGFBP4). IGFBP4is a protein that in humans is encoded by the IGFBP4 gene. This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.

 

Isotype:

Mouse IgG1

Species reactivity:

Mouse

Production:

Tissue culture

Purification:

Protein A/G

Applications:

ELISA etc.

Immunogen: 

Human IGFBP4

Storage: 

Store at +4°C short term (1-2 weeks). Store at -20°C long term.

Formulation:

PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug.

Clonality:

Monoclonal

 

References

1. Reynolds CM, et al. (2017). Manipulation of the Growth Hormone-Insulin-Like 

Growth Factor (GH-IGF) Axis: A Treatment Strategy to Reverse the Effects of Early Life Developmental Programming. Int J Mol Sci. Aug 8;18(8). pii: E1729.

2. Maridas DE, et al. (2017). IGFBP-4 regulates adult skeletal growth in a sex-specific manner. J Endocrinol. Apr;233(1):131-144.

3. Wu T, et al. (2016). Insulin-Like Growth Factor Binding Protein-4 as a Marker of Chronic Lupus Nephritis. PLoS One. Mar 28;11(3):e0151491

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