Valproic Acid

$107.00
In stock
Catalog
C10067
Bulk Inquiry

Valproic acid (VPA) is a histone deacetylase inhibitor with potent antitumor activity. Valproic acid treatment promotes histone acetylation allowing the chromatin to adopt a relaxed structure facilitating the binding of ectopically expressed transcription factors or downstream secondary factors.

Valproic acid was found to significantly enhance reprogramming efficiencies of OSKM-, OSK- and OS-infected fibroblasts, eliminating the need for the oncogenes c-Myc or Klf4.  Valproic acid is believed to induce global transcriptional changes, in particular upregulating embryonic stem cell-specific genes while downregulating MEF-specific genes.

Product Name:  

Valproic Acid

CAS #:

1069-66-5

Catalog#:

C10067

Molecular weight:

166.19

Formula:

  • C8H15NaO2

 

Purity :

>98%


Description

Valproic acid (VPA) is a histone deacetylase inhibitor with potent antitumor activity. Valproic acid treatment promotes histone acetylation allowing the chromatin to adopt a relaxed structure facilitating the binding of ectopically expressed transcription factors or downstream secondary factors.

Valproic acid was found to significantly enhance reprogramming efficiencies of OSKM-, OSK- and OS-infected fibroblasts, eliminating the need for the oncogenes c-Myc or Klf4.  Valproic acid is believed to induce global transcriptional changes, in particular upregulating embryonic stem cell-specific genes while downregulating MEF-specific genes.

there is no file attached to this product
Write Your Own Review
You're reviewing:Valproic Acid
Your Rating