Rat Tubule Cells

Introduction:

The proximal tubule cells (PTC) are one of the most common epithelial cells in kidney. They not only play important functions in maintaining normal kidney function, such as fluid, amino acid and sodium reabsorption, but also are involved in the pathological changes in the cortical tubulointerstitium.

We isolate and provide to the research community the primary cultures of proximal tubule cells from Sprague Dawley rats. These cells were cultured in extra low serum medium to eliminate the potential contamination of fibroblasts and cryo-preserved at the earliest passages (P0 to P1) to maintain their similarity to the PTCs in vivo. They can serve as a powerful tool to study renal cell function and assess drug induced toxicity.