Anti SARS-CoV-2 S2 Monoclonal Antibody
Description: The novel coronavirus family (SARS-CoV-2) is the pathogen that causes COVID-19. The virus belongs to Group B coronaviruses, whose nucleic acid is negative stranded RNA, which is the largest RNA virus in the genome. The virus has caused a large number of infections and deaths since its outbreak in Wuhan, China, in late December 2019. Spike protein S is the main glycoprotein on the surface of virus, which is responsible for binding with host cells and infecting cells. This protein can be divided into S1 and S2, S1 is responsible for receptor binding, S2 is responsible for membrane fusion. Specific monoclonal antibody against novel coronavirus S2 can be used as an important tool for conserved antigen analysis, rapid diagnosis and scientific research, and broad-spectrum antibodies with neutralizing activity have downstream medicine development potential.
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Isotype: |
Mouse IgG |
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Species reactivity: |
Mouse |
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Production: |
Tissue culture |
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Purification: |
Protein A/G |
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Applications: |
ELISA, WB, IFA, IHC, CLIA, LFA, IP |
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Immunogen: |
Sf9 express recombination SARS-CoV-2 S protein trimer |
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Storage: |
Store at +4°C short term (1-2 weeks). Store at -20°C long term. |
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Formulation: |
PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug. |
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Clonality: |
Monoclonal |
References
1. Zhu N, Zhang D, et al.(2020). A Novel Coronavirus from Patients with Pneumonia in China,2019N Eng l J Med. Feb 20;382(8):727-733.
2.Li Q, Guan X.et al.(2020). Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia. N Engl J Med. Jan 29.doi:10.1056/NEJMoa2001316.
3. Wrapp D, Wang N, et al. (2020). Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation. Science. Feb 19.
Intended for research use only. Not for human, therapeutic, or diagnostic applications.
The buyer cannot sell or otherwise transfer this product for Commercial Purposes without written approval of Humimmu LLC.
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