Anti-mouse IL-10

$199.00
In stock
Catalog
A10053
Bulk Inquiry

Anti-mouse IL-10

Clone JES5-2A5 Catalog#: A10053 

Description: The JES5-2A5 monoclonal antibody reacts with mouse IL-10. IL-10 is a 17-21 kDa cytokine which is primarily produced by monocytes and, to a lesser extent, Th2 cells, mast cells, T regulatory cells, and certain subsets of activated T and B cells. IL-10 has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II antigens, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-κB activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggest that this cytokine is an essential immunoregulator in the intestinal tract. The JES5-2A5 antibody has been shown to neutralize the bioactivity of natural or recombinant IL-10.

 

Isotype:

Rat IgG1

Species reactivity:

Mouse

Production:

Tissue culture

Purification:

Protein G

Recommended Isotype Control:

Rat IgG1 Isotype control

Applications:

in vivo IL-10 neutralization

in vitro IL-10 neutralization

Immunogen: 

Mouse IL-10

Storage: 

Store at +4°C short term (1-2 weeks). Store at -20°C long term.

Formulation:

PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug.

Clonality:

Monoclonal

there is no file attached to this product
Write Your Own Review
You're reviewing:Anti-mouse IL-10
Your Rating