Anti-mouse CD276 (B7-H3)

$599.00
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Catalog
A10115
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Anti-mouse CD276 (B7-H3)

Clone MJ18 Catalog#: A10115 

Description: The MJ18 monoclonal antibody reacts with mouse CD276 also known as B7-H3. CD276 is a type I transmembrane protein and a member of the B7 family of co-stimulatory proteins. CD276 is expressed weakly on activated lymphocytes, macrophages, dendritic cells, nasal and airway epithelial cells, osteoblasts, and some tumor cell lines. A soluble form of CD276 is also secreted by monocytes, dendritic cells, and activated T cells. The biological role of CD276 is still under investigation however, recent studies suggest a negative regulatory role for CD276 in T cell responses. The MJ18 antibody has been shown to block CD276 when administered in vivo.

 

Isotype:

Rat IgG1

Species reactivity:

Mouse

Production:

Tissue culture

Purification:

Protein G

Recommended Isotype Control:

Rat IgG1 Isotype control

Applications:

in vivo B7-H3 blockade

Flow Cytometry

Immunogen: 

CD276 / B7-H3 antibody was raised against mouse IgG2a Fc-CD276 (aa 1-242)

Storage: 

Store at +4°C short term (1-2 weeks). Store at -20°C long term.

Formulation:

PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug.

Clonality:

Monoclonal

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