Anti-Human CEACAM5 Monoclonal Antibody
Anti-Human CEACAM5 Monoclonal Antibody
Clone: Tusbio Catalog#: AB5755
Description:
CEACAM5, also known as CD66e, is an immune regulatory protein expressed in humans and some other mammals. It belongs to the CEA family, where proteins play a crucial role in cell adhesion and signal transduction. In recent years, the research of CEACAM5 in fields such as cancer, inflammation, and neuroscience has attracted widespread attention. This article will provide a detailed introduction to the basic characteristics, functions, and important roles of CEACAM5 protein in human diseases.The CEACAM5 protein is a transmembrane protein characterized by a extracellular IgV like domain, a transmembrane sequence, and an intracellular domain. This IgV like domain is the main region where CEACAM5 interacts with other members of the CEA family. During cell adhesion and signal transduction, CEACAM5 interacts with other ligands through its IgV like domain, affecting cell growth, migration, and differentiation.
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Reactivities: |
Human |
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Target: |
CEACAM5 |
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Clone: |
Tusbio |
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Isotype: |
Human IgG1(E356D/M358L/KDel)-kappa |
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Alternative Name: |
ravtansine; SAR408701; CD66e; Carcinoembryonic antigen (CEA); CEACAM5; 2254086-60-5 |
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Recommend Isotype Controls: |
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Recommended Dilution Buffer: |
ABDB-1002 or PBS, pH 7.4,Contains no stabilizers or preservatives. |
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Immunogen: |
N/A |
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Formulation: |
PBS, pH 7.4,Contains no stabilizers or preservatives |
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Endotoxin: |
<1EU/mg ,Determined by LAL gel clotting assay |
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Purity: |
>95% Determined by SDS-PAGE |
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Sterility: |
0.2 μM filtered |
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Expression System: |
CHO |
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Purification: |
Protein A |
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Clonality: |
Monoclonal |
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Storage: |
2 weeks, 2-8°C under sterile conditions after reconstitution. Avoid repeated freeze-thaw. -80°C for a long-term storage. |
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Protocol Information: |
Since applications vary, each investigator should use the application references as a guide to help estimate the appropriate dose or concentration. The dose or concentration can be further optimized experimentally in a dose response or titration experiment. |
Intended for research use only. Not for human, therapeutic, or diagnostic applications.
The buyer cannot sell or otherwise transfer this product for Commercial Purposes without written approval of Humimmu LLC.
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