Anti-Human CD40 Monoclonal Antibody, Clone: Dacebio
Anti-Human CD40 Monoclonal Antibody, Clone: Dacebio
Clone: Dacebio Catalog#: AB5590
Description:
The CD40 (also known as TNFRSF5) receptor and its ligand CD40L (also known as CD154) belong to the TNF/TNFR family. CD40 is a type I membrane glycoprotein, which was initially identified as a surface marker of bladder cancer cells and B cells. Later, it was found that CD40 was expressed on antigen presenting cells (APCs), including monocytes, macrophages and dendritic cells; CD40 is also expressed by B cells and platelets, as well as some non hematopoietic cell types such as fibroblasts, endothelial cells, and smooth muscle cells; Even some tumor cells express CD40.
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Reactivities: |
Human |
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Target: |
CD40 |
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Clone: |
Dacebio |
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Isotype: |
Human IgG1-kappa |
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Alternative Name: |
SGN-40; SGN40; huS2C6; SEA-40; 880486-59-9; Cluster of Differentiation 40; CD40/TNFR5; Anti-human CD40. |
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Recommend Isotype Controls: |
Anti-HEL Human IgG1-Kappa Isotype control |
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Recommended Dilution Buffer: |
ABDB-1002 or PBS, pH 7.4,Contains no stabilizers or preservatives. |
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Immunogen: |
N/A |
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Formulation: |
PBS, pH 7.4,Contains no stabilizers or preservatives |
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Endotoxin: |
<1EU/mg ,Determined by LAL gel clotting assay |
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Purity: |
>95% Determined by SDS-PAGE |
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Sterility: |
0.2 μM filtered |
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Expression System: |
CHO |
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Purification: |
Protein A |
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Clonality: |
Monoclonal |
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Storage: |
2 weeks, 2-8°C under sterile conditions after reconstitution. Avoid repeated freeze-thaw. -80°C for a long-term storage. |
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Protocol Information: |
Since applications vary, each investigator should use the application references as a guide to help estimate the appropriate dose or concentration. The dose or concentration can be further optimized experimentally in a dose response or titration experiment. |
Intended for research use only. Not for human, therapeutic, or diagnostic applications.
The buyer cannot sell or otherwise transfer this product for Commercial Purposes without written approval of Humimmu LLC.
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