Anti-Human CD14 Monoclonal Antibody
Anti-Human CD14 Monoclonal Antibody
Clone: Atibio Catalog#: AB5801
Description:
CD14 (cluster of differentiation 14), formerly known as MY23 antigen, is a surface antigen and a member of the cell surface glycoprotein family. The protein encoded by the CD14 gene is preferentially expressed in monocytes/macrophages. CD14 is a high affinity receptor for the complex of lipopolysaccharide LPS and LPS binding protein (LBP) in Gram negative bacteria. CD14 recognizes and binds to LPS, causing cell tyrosine phosphorylation and nuclear factor NF- κ B translocation, triggering cytokine release, and oxygen free radical production play important roles in a series of reactions caused by the body's immune and defense systems.
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Reactivities: |
Human |
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Target: |
CD14 |
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Clone: |
Atibio |
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Isotype: |
Human IgG4-kappa |
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Alternative Name: |
IC14; anti CD14; soluble CD14 antibody; antigen CD14; LPS R; Cluster of differentiation 14 |
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Recommend Isotype Controls: |
Anti-HEL Human IgG4-Kappa Isotype control |
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Recommended Dilution Buffer: |
ABDB-1002 or PBS, pH 7.4,Contains no stabilizers or preservatives. |
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Immunogen: |
N/A |
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Formulation: |
PBS, pH 7.4,Contains no stabilizers or preservatives |
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Endotoxin: |
<1EU/mg ,Determined by LAL gel clotting assay |
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Purity: |
>95% Determined by SDS-PAGE |
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Sterility: |
0.2 μM filtered |
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Expression System: |
CHO |
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Purification: |
Protein A |
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Clonality: |
Monoclonal |
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Storage: |
2 weeks, 2-8°C under sterile conditions after reconstitution. Avoid repeated freeze-thaw. -80°C for a long-term storage. |
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Protocol Information: |
Since applications vary, each investigator should use the application references as a guide to help estimate the appropriate dose or concentration. The dose or concentration can be further optimized experimentally in a dose response or titration experiment. |
Intended for research use only. Not for human, therapeutic, or diagnostic applications.
The buyer cannot sell or otherwise transfer this product for Commercial Purposes without written approval of Humimmu LLC.
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