Description: Monkeypox virus (MPXV) is a double-stranded DNA virus of the Orthopoxvirus genus of the family Poxviridae.Two genetic clades of the monkeypox virus have been characterized: West African and Central African. MPXV is one of the 4 orthopoxvirus species pathogenic for humans, the other 3 being variola major virus (VARV), the causative agent of smallpox, now eradicated, variola minor virus, and cowpox virus (CPXV). A35R can be used in a simple heat-inactivated serological enzyme-linked immunosorbent assay for the identification of recent MPXV infection.
Isotype: |
Mouse IgG2a |
Species reactivity: |
Mouse |
Production: |
Tissue culture |
Purification: |
Protein A/G |
Applications: |
ELISA, IFA, FACS, WB, ICA |
Immunogen: |
E.Coli expressed MPXV-A35R protein antigen |
Storage: |
Store at +4°C short term (1-2 weeks). Store at -20°C long term. |
Formulation: |
PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug. |
Clonality: |
Monoclonal |
Reference:
1.Adler H, Gould S, et al.(2022). Clinical features and management of humanmonkeypox: a retrospective observational study in the UK Lancet Infect Dis.Aug;22(8):1153-1162
2.Thornhill P, Barkati S, et al. (2022). Monkeypox Virus Infection in Humansacross 16 Countries - April-June 2022.N EnglJ Med.Jul 21.
3.Petersen E, Kantele A, et al.(2019). Human Monkeypox: Epidemiologic andClinical Characteristics, Diagnosis, and Prevention. Infect Dis Clin North Am.Dec;33(4):1027-1043.
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