Anti Human Tau protein (hTau) Monoclonal Antibody
Anti Human Tau protein (hTau) Monoclonal Antibody
Clone HI562 Catalog#: A50562
Description: The Human Tau protein is a microtubule-associated protein (MAP) that is expressed in the brain and is involved in a variety of important cellular processes. It is encoded by the MAPT gene, which is located on chromosome 17.
Tau proteins play a critical role in maintaining the stability of microtubules, which are cylindrical structures that form the cytoskeleton of cells. Microtubules serve as tracks for the transport of various cellular materials, including neurotransmitter vesicles, which are essential for communication between nerve cells. In neurons, Tau proteins bind to microtubules and help to stabilize them, allowing for the proper formation and maintenance of the neuronal cytoskeleton. This stability is crucial for the structural integrity of neurons and for the efficient transport of materials within them. Tau proteins are also involved in other important processes, such as cell division, and have been found to play a role in the development of neurodegenerative diseases, such as Alzheimer's disease. In these diseases, Tau proteins can become abnormally phosphorylated, leading to the formation of aggregates called neurofibrillary tangles, which are a characteristic feature of the disease.
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Isotype: |
Mouse IgG |
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Species reactivity: |
Mouse |
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Production: |
Tissue culture |
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Purification: |
Protein A/G |
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Applications: |
ELISA, WB, IFA, IHC, CLIA, LFA, IP |
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Immunogen: |
Recombinant human Tau protein |
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Storage: |
Store at +4°C short term (1-2 weeks). Store at -20°C long term. |
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Formulation: |
PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug. |
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Clonality: |
Monoclonal |
Intended for research use only. Not for human, therapeutic, or diagnostic applications.
The buyer cannot sell or otherwise transfer this product for Commercial Purposes without written approval of Humimmu LLC.
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