Anti Human Papillomavirus (HPV16/E6) Monoclonal Antibody
Clone HI372 Catalog#: A350022 Datasheet
Description: The Human Papillomavirus (HPV) is a non-enveloped, double-stranded, circular DNA virus of the Papillomaviridae family. HPV is the cause of 5% of all cancers. HPV16 and HPV18, the two most common high-risk HPVs, are responsible for ~70% of all HPV-related cervical cancers and head and neck cancers.
Isotype: |
IgG |
Species reactivity: |
Mouse |
Production: |
Tissue culture |
Purification: |
Protein A/G |
Applications: |
Neutralization assay, ELISA, IFA, Bilateral flow, etc |
Immunogen: |
E.coli expressed recombinant HPV16/E6 protein |
Storage: |
Store at +4°C short term (1-2 weeks). Store at -20°C long term. |
Formulation: |
PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug. |
Clonality: |
Monoclonal |
Reference:
1.Stanley M.(2010). Pathology and epidemiology of HPV infection in females. Gynecol Oncol. May;117(2 Suppl):S5-10.
2.Yugawa T, Kiyono T.(2009). Molecular mechanisms of cervical carcinogenesis by high-risk human papillomaviruses: novel functions of E6 and E7 oncoproteins. Rev Med Virol. Mar;19(2):97-113.
3.Zheng Y, Li X, et al. (2022). High-Risk Human Papillomavirus Oncogenic E6/E7 mRNAs Splicing Regulation. Front Cell Infect Microbiol. Jun27;12:929666.
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