Anti-Human IL-6 Monoclonal Antibody
Anti-Human IL-6 Monoclonal Antibody
Clone: Silbio Catalog#: AB5850
Description:
The interleukin-6 (IL-6), is a multifunctional cytokine with diverse functions. IL-6 can regulate the growth and differentiation of various cells, playing an important role in regulating immune responses, acute phase reactions, and hematopoiesis. It also plays a crucial role in the body's anti-infection immune response. IL-6 levels are significantly altered in various diseases, and its expression dysregulation can lead to many diseases. The main clinical manifestation of IL-6 level elevation is when the disease occurs. During acute inflammatory reactions such as internal or external injury, surgery, stress reactions, infection, brain death, tumor production, and other situations, IL-6 is rapidly generated. The serum concentration level of IL-6 increases earlier than that of PCT and CRP, and can serve as an early warning indicator for sepsis. IL-6 also plays an important role in chronic inflammatory reactions such as rheumatoid arthritis.
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Reactivities: |
Human |
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Target: |
IL-6 |
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Clone: |
Silbio |
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Isotype: |
Human IgG1(E356D/M358L)-kappa |
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Alternative Name: |
CLLB8,CNTO 328; B-cell differentiation factor; B-cell stimulatory factor 2; BSF2; BSF-2; CDF; CTL differentiation factor ; HSF; hybridoma growth factor; IFNB2; IFN-beta-2; IL6; IL-6; Interferon beta-2; interleukin 6 |
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Recommend Isotype Controls: |
Anti-HEL Human IgG1(E356D/M358L)-Kappa Isotype control |
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Recommended Dilution Buffer: |
ABDB-1002 or PBS, pH 7.4,Contains no stabilizers or preservatives. |
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Immunogen: |
N/A |
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Formulation: |
PBS, pH 7.4,Contains no stabilizers or preservatives |
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Endotoxin: |
<1EU/mg ,Determined by LAL gel clotting assay |
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Purity: |
>95% Determined by SDS-PAGE |
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Sterility: |
0.2 μM filtered |
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Expression System: |
CHO |
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Purification: |
Protein A |
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Clonality: |
Monoclonal |
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Storage: |
2 weeks, 2-8°C under sterile conditions after reconstitution. Avoid repeated freeze-thaw. -80°C for a long-term storage. |
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Protocol Information: |
Since applications vary, each investigator should use the application references as a guide to help estimate the appropriate dose or concentration. The dose or concentration can be further optimized experimentally in a dose response or titration experiment. |
Intended for research use only. Not for human, therapeutic, or diagnostic applications.
The buyer cannot sell or otherwise transfer this product for Commercial Purposes without written approval of Humimmu LLC.
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