Broadly neutralizing antibodies against influenza A viruses, Fully human, FI6, MEDI8852
Broadly neutralizing antibodies against influenza A viruses, Fully human, FI6, MEDI8852
Clone FI6 Catalog#: A90002
Description: FI6 (MEDI8852) is fully human neutralizing monoclonal antibody against influenza A. FI6 recognizes the hemagglutinin (HA) glycoprotein of all 16 subtypes and neutralized both group 1 and group 2influenza A viruses. FI6 may be used for passive protection and to inform vaccine design because of its broad specificity and neutralization potency..
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Isotype: |
IgG1 |
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Species reactivity: |
Human |
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Production: |
Tissue culture |
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Purification: |
Protein A |
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Applications: |
Neutralization assay, In vivo protection etc. |
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Storage: |
Store at +4°C short term (1-2 weeks). Store at -20°C long term. |
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Formulation: |
PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug. |
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Clonality: |
Monoclonal |
Reference:
- Corti D, et al. (2011). A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins.Science. 2011 Aug 12;333(6044):850-6.
- Kallewaard NL, et al. (2016). Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes.Cell. 2016 Jul 28;166(3):596-608.
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