Broadly neutralizing antibodies against influenza A viruses, Fully human, CR8020
Broadly neutralizing antibodies against influenza A viruses, Fully human, CR8020
Clone CR8020 Catalog#: A90005
Description: CR8020is fully human neutralizing monoclonal antibody against on group 2 influenza A. CR8020 with broad neutralizing activity against most group 2 viruses, including H3N2 and H7N7, which cause severe human infection.
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Isotype: |
IgG1 |
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Species reactivity: |
Human |
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Production: |
Tissue culture |
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Purification: |
Protein A |
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Applications: |
Neutralization assay, In vivo protection etc. |
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Storage: |
Store at +4°C short term (1-2 weeks). Store at -20°C long term. |
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Formulation: |
PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug. |
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Clonality: |
Monoclonal |
Reference:
- Ekiert DC, et al. (2011). A highly conserved neutralizing epitope on group 2 influenza A viruses. Science. 2011 Aug 12;333(6044):843-50.
- Tharakaraman K, et al. (2014). Broadly neutralizing influenza hemagglutinin stem-specific antibody CR8020 targets residues that are prone to escape due to host selection pressure.Cell Host Microbe. 2014 May 14;15(5):644-51.
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