Anti Monkeypox Virus (MPXV-A29L) antibody, Clone HI33
Description: Monkeypox virus (MPXV) is a double-stranded DNA virus of the Orthopoxvirus genus of the family Poxviridae.Two genetic clades of the monkeypox virus have been characterized: West African and Central African. MPXV is one of the 4 orthopoxvirus species pathogenic for humans, the other 3 being variola major virus (VARV), the causative agent of smallpox, now eradicated, variola minor virus, and cowpox virus (CPXV). There is a range of animal poxviruses, several of which have zoonotic potential. Infections in humans have been described for vaccinia virus, cowpox virus, buffalopox virus, and sporadic cases of camelpox. Monkeypox infects a wide range of mammalian species, but its natural host reservoir remains unknown. A29L is conserved antigen of inner mature virion of MPXV, which is genetically similar as A27 antigen of VACA.
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Isotype: |
Mouse IgG2a |
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Species reactivity: |
Mouse |
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Production: |
Tissue culture |
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Purification: |
Protein A/G |
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Applications: |
ELISA, IF,etc. |
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Immunogen: |
AAV8 and AAV9 virus |
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Storage: |
Store at +4°C short term (1-2 weeks). Store at -20°C long term. |
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Formulation: |
PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug. |
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Clonality: |
Monoclonal |
Reference:
1.Adler H, Gould S, et al. (2022). Clinical features and management of human monkeypox: a retrospective observational study in the UK. Lancet Infect Dis. Aug;22(8):1153-1162.
2.Thornhill JP, Barkati S, et al. (2022). Monkeypox Virus Infection in Humans across 16 Countries - April-June 2022. N Engl J Med. Jul 21.
3.Petersen E, Kantele A, et al. (2019). Human Monkeypox: Epidemiologic and Clinical Characteristics, Diagnosis, and Prevention. Infect Dis Clin North Am. Dec;33(4):1027-1043.
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