Anti-mouse IL-17A (Clone 17F3)
Anti-mouse IL-17A
Clone 17F3 Catalog#: A10154
Description: IL17A is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
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Isotype: |
Mouse IgG1 |
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Species reactivity: |
Mouse |
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Production: |
Tissue culture |
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Purification: |
Protein G |
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Recommended Isotype Control: |
Mouse IgG1 Isotype control |
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Applications: |
In vivo IL-17A neutralization |
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Immunogen: |
E. coli expressed recombinant protein |
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Storage: |
Store at +4°C short term (1-2 weeks). Store at -20°C long term. |
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Formulation: |
PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug. |
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Clonality: |
Monoclonal |
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