Anti-Human TROP2 Monoclonal Antibody
Anti-Human TROP2 Monoclonal Antibody
Clone: Sacbio Catalog#:AB5323
Description:
TROP2 is a cancer-related antigen that is expressed at low levels in normal tissues and overexpressed in various malignant tumors. It is mainly expressed in various human epithelial cancers, including breast cancer, lung cancer, gastric cancer, colorectal cancer, pancreatic cancer, prostate cancer, cervical cancer, head and neck cancer, and ovarian cancer. The expression level of TROP2 is related to the degree of malignancy of the disease. Overexpression of TROP2 can promote tumor cell growth, proliferation, and metastasis. This differential expression of TROP2 protein makes it a new target for researchers to develop antibody-conjugated drugs.
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Reactivities: |
Human |
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Target: |
TROP2 |
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Clone: |
Sacbio |
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Isotype: |
Human IgG1(E356D/M358L)-kappa |
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Alternative Name: |
;Hrs7;Cell surface glycoprotein Trop-2; EGP1; EGP-1; epithelial glycoprotein-1; GA733-1; GA733-1GP50; gastrointestinal tumor-associated antigen GA7331;gp50; M1S1cell surface glycoprotein TROP2; |
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Recommend Isotype Controls: |
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Recommended Dilution Buffer: |
ABDB-1002 or PBS, pH 7.4,Contains no stabilizers or preservatives. |
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Immunogen: |
N/A |
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Formulation: |
PBS, pH 7.4,Contains no stabilizers or preservatives |
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Endotoxin: |
<1EU/mg ,Determined by LAL gel clotting assay |
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Purity: |
>95% Determined by SDS-PAGE |
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Sterility: |
0.2 μM filtered |
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Expression System: |
CHO |
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Purification: |
Protein A |
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Clonality: |
Monoclonal |
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Storage: |
2 weeks, 2-8°C under sterile conditions after reconstitution. Avoid repeated freeze-thaw. -80°C for a long-term storage. |
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Protocol Information: |
Since applications vary, each investigator should use the application references as a guide to help estimate the appropriate dose or concentration. The dose or concentration can be further optimized experimentally in a dose response or titration experiment. |
Intended for research use only. Not for human, therapeutic, or diagnostic applications.
The buyer cannot sell or otherwise transfer this product for Commercial Purposes without written approval of Humimmu LLC.
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