Anti-Human CD51 Monoclonal Antibody
Anti-Human CD51 Monoclonal Antibody
Clone: Abibio Catalog#:AB5332
Description:
Among the integrin family members, integrin αv (CD51) has been attracting much attention due to its role in tumor metastasis. FAK is the major downstream kinase of CD51 and can predict the survival outcome of HCC patients. In addition, several CD51 ligands including osteopontin (OPN) and fibronectin (FN) have been identified as the major proteins characterizing metastatic HCC and can serve as predictors of tumor recurrence after liver transplantation.
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Reactivities: |
Human |
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Target: |
CD51 |
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Clone: |
Abibio |
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Isotype: |
Human IgG1-kappa |
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Alternative Name: |
DI-17E6,DI17E6,EMD 525797;antigen identified by monoclonal L230; CD51 antigen; CD51; Integrin alpha V; integrin alpha-V; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); ITGAV; MSK8; Vitronectin Receptor alpha; Vitronectin receptor subunit alpha; VNRA; VNRADKFZp686A08142 |
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Recommend Isotype Controls: |
Anti-HEL Human IgG1-Kappa Isotype control |
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Recommended Dilution Buffer: |
ABDB-1002 or PBS, pH 7.4,Contains no stabilizers or preservatives. |
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Immunogen: |
N/A |
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Formulation: |
PBS, pH 7.4,Contains no stabilizers or preservatives |
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Endotoxin: |
<1EU/mg ,Determined by LAL gel clotting assay |
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Purity: |
>95% Determined by SDS-PAGE |
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Sterility: |
0.2 μM filtered |
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Expression System: |
CHO |
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Purification: |
Protein A |
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Clonality: |
Monoclonal |
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Storage: |
2 weeks, 2-8°C under sterile conditions after reconstitution. Avoid repeated freeze-thaw. -80°C for a long-term storage. |
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Protocol Information: |
Since applications vary, each investigator should use the application references as a guide to help estimate the appropriate dose or concentration. The dose or concentration can be further optimized experimentally in a dose response or titration experiment. |
Intended for research use only. Not for human, therapeutic, or diagnostic applications.
The buyer cannot sell or otherwise transfer this product for Commercial Purposes without written approval of Humimmu LLC.
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