Anti-human CD4 [OKT-4]

$599.00
In stock
Catalog
A10007
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Anti-human CD4 [OKT-4]

Clone: OKT-4 Catalog#: A10007

Description: The OKT-4 monoclonal antibody reacts with the human CD4. The CD4 antigen is a 55 kDa cell surface type I membrane glycoprotein belonging to the immunoglobulin superfamily. CD4 acts as a co-receptor which in cooperation with the T cell receptor (TCR) interacts with class II MHC molecules displayed by antigen presenting cells (APC). CD4 is expressed by the majority of thymocytes, most helper T cells, a subset of NK-T cells and weakly by dendritic cells and macrophages. CD4 plays an important role in the development of T cells and is required for mature T cells to function optimally.

 

Isotype:

Mouse IgG2b

Species reactivity:

Human

Production:

Tissue culture

Purification:

Protein G

Recommended Isotype Control:

Mouse IgG2b Isotype control

Applications:

in vitro T cell stimulation/activation

in vivo CD4+ T cell depletion in humanized mice

Flow cytometry

Immunoprecipitation

Immunogen: 

human CD4

Storage: 

Store at +4°C short term (1-2 weeks). Store at -20°C long term.

Formulation:

PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug.

Clonality:

Monoclonal

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