Anti-mouse CD4 antibody

$599.00
In stock
Catalog
A10006
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Anti-mouse CD4 antibody

Clone: GK1.5 Catalog#: A10006

 

Description: The GK1.5 monoclonal antibody reacts with the mouse CD4. The CD4 antigen is a 55 kDa cell surface type I membrane glycoprotein belonging to the immunoglobulin superfamily. CD4 acts as a co-receptor which in cooperation with the T cell receptor (TCR) interacts with class II MHC molecules displayed by antigen presenting cells (APC). CD4 is expressed by the majority of thymocytes, most helper T cells, a subset of NK-T cells and weakly by dendritic cells and macrophages. CD4 plays an important role in the development of T cells and is required for mature T cells to function optimally. The GK1.5 antibody has been shown to compete with clones YTS 177 and YTS 191 for CD4 binding.

 

Isotype:

Rat IgG2b

Species reactivity:

Mouse

Production:

Tissue culture

Purification:

Protein G

Recommended Isotype Control:

Rat IgG2b Isotype control

Applications:

in vivo CD4+ T cell depletionFlow cytometryWestern blot

Immunogen: 

Mouse CTL clone V4

Storage: 

Store at +4°C short term (1-2 weeks). Store at -20°C long term.

Formulation:

PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug.

Clonality:

Monoclonal

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