Anti- human CD3 [UCHT1] antibody

$499.00
In stock
Catalog
A10003
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Anti- human CD3 [UCHT1]

Clone: UCHT 1      Catalog#: A10003

Description: The UCHT1 monoclonal antibody reacts with human CD3e, a 20 kDa subunit of the TCR complex. Along with the other CD3 subunits gamma and delta, the epsilon chain is required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Crosslinking of TCR via immobilized UCHT1 initiates an intracellular biochemical pathway resulting in cellular activation and proliferation.

 

Isotype:

IgG1

Species reactivity:

Human

Production:

Tissue culture

Purification:

ProteinG purified

Recommended Isotype Control:

Mouse IgG1 Isotype control

Applications:

in vivo T cell depletion humanized mice       

ex vivo T cell inhibiton for xenografts
Flow cytometry

Immunogen: 

Human placenta FcR

Storage: 

Store at +4°C short term (1-2 weeks). Store at -20°C long term.

Formulation:

PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug.

Clonality:

Molyclonal

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