Anti-mouse CD3 epsilon [145-2C11] antibody

$599.00
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Catalog
A10002
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Anti-mouse CD3 epsilon [145-2C11] antibody

Clone: 145-2C11      Catalog#: A10002 

Description: The 145-2C11 monoclonal antibody reacts with mouse CD3 epsilon, a 20 kDa subunit of the TCR complex. Along with the other CD3 subunits, gamma and delta, the epsilon chain is required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Binding of 145-2C11 to TCR initiates the intracellular biochemical pathway resulting in cellular activation, proliferation, and apoptosis depending on specific conditions utilized. 145-2C11 is commonly used as a phenotypic marker for mouse T cells.

 

Isotype:

Armenian Hamster IgG

Species reactivity:

Mouse

Production:

Tissue culture

Purification:

Functional Grade Purified

Recommended Isotype Control:

Armenian Hamster IgG

Applications:

in vivo T cell depletion

in vitro T cell stimulation/activation

Flow cytometry

Western blot

Immunogen: 

H-2Kb specific cytotoxic T lymphocyte clone BM10-37

Storage: 

Store at +4°C short term (1-2 weeks). Store at -20°C long term.

Formulation:

Aqueous buffer, no sodium azide

Clonality:

Monoclonal

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