Anti-mouse CD3 epsilon [145-2C11] antibody

Anti-mouse CD3 epsilon [145-2C11] antibody
Clone: 145-2C11 Catalog#: A10002
Description: The 145-2C11 monoclonal antibody reacts with mouse CD3 epsilon, a 20 kDa subunit of the TCR complex. Along with the other CD3 subunits, gamma and delta, the epsilon chain is required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Binding of 145-2C11 to TCR initiates the intracellular biochemical pathway resulting in cellular activation, proliferation, and apoptosis depending on specific conditions utilized. 145-2C11 is commonly used as a phenotypic marker for mouse T cells.
Isotype: |
Armenian Hamster IgG |
Species reactivity: |
Mouse |
Production: |
Tissue culture |
Purification: |
Functional Grade Purified |
Recommended Isotype Control: |
Armenian Hamster IgG |
Applications: |
in vivo T cell depletion in vitro T cell stimulation/activation Flow cytometry Western blot |
Immunogen: |
H-2Kb specific cytotoxic T lymphocyte clone BM10-37 |
Storage: |
Store at +4°C short term (1-2 weeks). Store at -20°C long term. |
Formulation: |
Aqueous buffer, no sodium azide |
Clonality: |
Monoclonal |