Anti-mouse NK1.1

$199.00
In stock
Catalog
A10043
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Anti-mouse NK1.1

Clone PK136 Catalog#: A10043 

Description: The PK136 monoclonal antibody reacts with mouse NK1.1 also known as CD161b/CD161c, KLRB1, NKR-P1A and Ly-55. NK1.1 is a type II integral membrane glycoprotein with a C-type lectin domain and is encoded by the Klrb1c/NKR-P1C gene. NK1.1 plays roles in NK cell activation and differentiation, IFN-γ production, cytotoxic granule release, and is thought to be involved in the generation of Th2 cells. NK1.1 is predominantly expressed as a disulfide-linked homodimer on NK cells however, it is also expressed on NK-T cells, a rare population of T lymphocytes. NK 1.1 is only expressed by C57BL/6, FVB/N, and NZB strains of mice and not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129 strains.

 

Isotype:

Mouse IgG2a

Species reactivity:

Mouse

Production:

Tissue culture

Purification:

Protein A

Recommended Isotype Control:

Mouse IgG2a Isotype control

Applications:

in vivo NK cell depletion    

Flow cytometry

Immunogen: 

Mouse NK-1+ Spleen and Bone Marrow Cells

Storage: 

Store at +4°C short term (1-2 weeks). Store at -20°C long term.

Formulation:

PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug.

Clonality:

Monoclonal

 

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