Anti-mouse LPAM-1 (Integrin α4β7)

$199.00
In stock
Catalog
A10041
Bulk Inquiry

Anti-mouse LPAM-1 (Integrin α4β7)

Clone DATK32  Catalog#: A10041 

Description: Integrin beta 7 associates with integrin alpha 4 (CD49d) to form the alpha 4 beta 7 integrin LPAM-1, expressed on intraepithelial lymphocytes. It also associates with alpha E (CD103) to form the alpha E beta 7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Ligands for LPAM-1 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the ligand of HML-1 is E-cadherin (CD324). Integrin beta 7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response.

 

Isotype:

Rat IgG2a

Species reactivity:

Mouse

Production:

Tissue culture

Purification:

Protein G

Recommended Isotype Control:

Rat IgG2a Isotype control

Applications:

in vivo Integrin α4β7 neutralization         

Flow cytometry

Immunogen: 

Mouse LPAM-1

Storage: 

Store at +4°C short term (1-2 weeks). Store at -20°C long term.

Formulation:

PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug.

Clonality:

Monoclonal

there is no file attached to this product
Write Your Own Review
You're reviewing:Anti-mouse LPAM-1 (Integrin α4β7)
Your Rating