Anti-mouse OX40L (CD134L)
Clone RM134L Catalog#: A10039
Description: The RM134L monoclonal antibody reacts with mouse OX-40L also known as CD134L. OX-40L is a 35 kDa member of the TNF superfamily that is expressed on activated B cells and antigen presenting cells. OX40L is the ligand for OX-40 (CD134). OX-40 signaling regulates both CD4 and CD8 T cell clonal expansion. It provides a costimulatory signal to an antigen-reacting naive T cells to prolong proliferation, as well as augment the production of several cytokines including IL-2. In vivo treatment with the RM134L antibody has been shown to inhibit the poly(I:C)/CD40 stimulated proliferation of CD4 T cells.
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Isotype: |
Rat IgG2b |
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Species reactivity: |
Mouse |
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Production: |
Tissue culture |
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Purification: |
Protein G |
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Recommended Isotype Control: |
Rat IgG2b Isotype control |
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Applications: |
in vivo blocking of OX40/OX40L signaling in vitro OX40L neutralization |
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Immunogen: |
Rat NRK-52E cell line transfected with mouse OX-40L |
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Storage: |
Store at +4°C short term (1-2 weeks). Store at -20°C long term. |
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Formulation: |
PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug. |
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Clonality: |
Monoclonal |