Anti-mouse CD28 antibody

$599.00
In stock
Catalog
A10020
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Anti-mouse CD28 antibody

Clone: 37.51 Catalog#: A10020

 

Description: The 37.51 monoclonal antibody reacts with mouse CD28, a 45 kDa costimulatory receptor and a member of the Ig superfamily. CD28 is expressed by thymocytes, most peripheral T cells, and NK cells. CD28 is a receptor for CD80 (B7-1) and CD86 (B7-2). Signaling through CD28 augments IL-2 and IL-2 receptor expression as well as cytotoxicity of CD3-activated T cells. The 37.51 antibody has been shown to stimulate the proliferation and cytokine production by activated T and NK cells and provide a costimulatory signal for CTL induction.

 

Isotype:

Syrian Hamster IgG2

Species reactivity:

Mouse

Production:

Tissue culture

Purification:

Protein G

Recommended Isotype Control:

Polyclonal Syrian Hamster IgG

Applications:

in vitro  T cell stimulation/activation        

in vivo CD28 blockade

Immunogen: 

Mouse EL-4 (T-cell lymphoma) Cells

Storage: 

Store at +4°C short term (1-2 weeks). Store at -20°C long term.

Formulation:

PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug.

Clonality:

Monoclonal

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