Anti-human CD25 (IL-2Rα) [7G7B6] antibody

Anti-human CD25 (IL-2Rα) [7G7B6] antibody
Clone: 7G7B6 Catalog#: A10019
Description: The 7G7B6 monoclonal antibody reacts with human IL-2Rα also known as CD25, Ly-43, p55, or Tac. IL-2Rα is the 55 kDa ligand-binding subunit of the interleukin 2 receptor alpha chain. IL-2Rα is expressed on activated mature T and B lymphocytes, thymocyte subsets, pre-B cells, and T regulatory cells. IL-2Rα has been shown to play roles in lymphocyte differentiation, activation, and proliferation. Alone, the IL-2Rα binds IL-2 with relatively low affinity however, when IL-2Rα associates with IL-2Rβ (CD122) and the common gamma chain (CD132) the complex binds IL-2 with high affinity.
Isotype: |
Mouse IgG2a |
Species reactivity: |
Human |
Production: |
Tissue culture |
Purification: |
Protein G |
Recommended Isotype Control: |
Mouse IgG2a Isotype control |
Applications: |
Immunoprecipitation Immunofluorescence |
Immunogen: |
Stimulated PBMC |
Storage: |
Store at +4°C short term (1-2 weeks). Store at -20°C long term. |
Formulation: |
PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug. |
Clonality: |
Monoclonal |