Anti-mouse CD25 (IL-2Rα) [7D4]

$199.00
In stock
Catalog
A10018
Bulk Inquiry

Anti-mouse CD25 (IL-2Rα) [7D4]

Clone: 7D4 Catalog#: A10018

 

Description: The 7D4 monoclonal antibody reacts with mouse IL-2Rα also known as CD25, Ly-43, p55, or Tac. IL-2Rα is the 55 kDa ligand-binding subunit of the interleukin 2 receptor alpha chain. IL-2Rα is expressed on activated mature T and B lymphocytes, thymocyte subsets, pre-B cells, and T regulatory cells. IL-2Rα has been shown to play roles in lymphocyte differentiation, activation, and proliferation. Alone, the IL-2Rα binds IL-2 with relatively low affinity however, when IL-2Rα associates with IL-2Rβ (CD122) and the common gamma chain (CD132) the complex binds IL-2 with high affinity. The 7D4 antibody recognizes a different epitope on CD25 than the PC-61.5.3 clone.

 

Isotype:

Rat IgM

Species reactivity:

Mouse

Production:

Tissue culture

Purification:

T-Gel

Recommended Isotype Control:

Rat IgM control

Applications:

in vivo regulatory T cell inactivation

Immunogen: 

IL-2-dependent BALB/c mouse helper T-cell clone HT-2

Storage: 

Store at +4°C short term (1-2 weeks). Store at -20°C long term.

Formulation:

PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug.

Clonality:

Monoclonal

there is no file attached to this product
Write Your Own Review
You're reviewing:Anti-mouse CD25 (IL-2Rα) [7D4]
Your Rating