Anti-mouse CD11b antibody

$699.00
In stock
Catalog
A10014
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Anti-mouse CD11b antibody

Clone: M1/70 Catalog#: A10014

 

Description: The M1/70 monoclonal antibody reacts with mouse CD11b, a 170 kDa membrane glycoprotein also known as integrin alpha M (ITGAM). CD11b belongs to the integrin alpha family and is primarily expressed on granulocytes and monocytes/macrophages but also expressed on dendritic cells, NK cells, and subsets of T and B cells. CD11b and CD18 combine to form Mac-1. Mac-1 functions as a complement receptor as well as a receptor for fibrinogen, factor X, and ICAM1.

 

Isotype:

Rat IgG2b

Species reactivity:

Mouse

Production:

Tissue culture

Purification:

Protein G

Recommended Isotype Control:

Rat IgG2b Isotype control

Applications:

in vivo CD11b neutralization         

ILC2 cell purification          

Flow cytometry

Immunogen: 

Immunization with C57BL/10 splenocytes

Storage: 

Store at +4°C short term (1-2 weeks). Store at -20°C long term.

Formulation:

PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug.

Clonality:

Monoclonal

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