Product Name:  

5-Aza-2'-deoxycytidine

"/> 5-Aza-2'-deoxycytidine

5-Aza-2'-deoxycytidine

$218.00
In stock
Catalog
C10062
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5-Aza-2’-deoxycytidine (5-AzadCyD, 5-Aza-CdR, decitabine) is a specific inhibitor of DNA methylation. It functions in a similar manner to aza-citidine, although decitabine can only be incorporated into DNA strands while azacitidine can be incorporated into both DNA and RNA chains.

5-AzadCyD is a prodrug that requires activation via phosphorylation by deoxycytidine kinase. The nucleotide analog is incorporated into DNA, where it produces an irreversible inactivation of DNA methyltransferase. 5-AzadCyD was demonstrated to be a potent antineoplastic agent against leukemia and tumors in animal models.

Product Name:  

5-Aza-2'-deoxycytidine

CAS #:

2353-33-5

Catalog#:

C10062

Molecular weight:

228.2

Formula:

C8H12N4O4

Purity :

>98%

 

Description

5-Aza-2’-deoxycytidine (5-AzadCyD, 5-Aza-CdR, decitabine) is a specific inhibitor of DNA methylation. It functions in a similar manner to aza-citidine, although decitabine can only be incorporated into DNA strands while azacitidine can be incorporated into both DNA and RNA chains.

5-AzadCyD is a prodrug that requires activation via phosphorylation by deoxycytidine kinase. The nucleotide analog is incorporated into DNA, where it produces an irreversible inactivation of DNA methyltransferase. 5-AzadCyD was demonstrated to be a potent antineoplastic agent against leukemia and tumors in animal models.

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