Product Name:  

AG490 AG490

JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.

AG490

$135.00
In stock
Catalog
C10057
Bulk Inquiry

AG490 is a specific and potent inhibitor of the Janus kinase 2 protein (JAK2). JAK2 regulates the phosphorylation of JNK, primarily through PI3K. It has been established that JAK2 plays an important role in TLR-mediated biological responses, blocking TLR4-mediated responses to LPS and TLR5-mediated responses to flagellin. JAK2 is also involved in cytokine signaling, such as IL-2, IL-6 and IL-12.

 

Product Name:  

AG490

CAS #:

133550-30-8

Catalog#:

C10057

Molecular weight:

294.3

Formula:

C17H14N2O3

Purity :

>98%

Description

AG490 is a specific and potent inhibitor of the Janus kinase 2 protein (JAK2). JAK2 regulates the phosphorylation of JNK, primarily through PI3K. It has been established that JAK2 plays an important role in TLR-mediated biological responses, blocking TLR4-mediated responses to LPS and TLR5-mediated responses to flagellin. JAK2 is also involved in cytokine signaling, such as IL-2, IL-6 and IL-12.

 

there is no file attached to this product
Write Your Own Review
You're reviewing:AG490
Your Rating