Product Name:  

SP600125

SP600125

SP600125

$135.00
In stock
Catalog
C10043
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SP600125 is a potent, cell-permeable, selective and reversible inhibitor of c-Jun N-terminal kinase (JNK).

 

It inhibits in a dose-dependent manner the phosphorylation of JNK. JNK is a member of the mitogen-activated protein kinase (MAPK) family and plays an essential role in TLR mediated inflammatory responses.

 

Inhibition of JNK activity by SP600125 is usually associated with downregulation of Beclin-1 and reduced autophagy.

Product Name:  

SP600125

CAS #:

129-56-6

Catalog#:

C10043

Molecular weight:

220.2

Formula:

C₁₄H₈N₂O

Purity :

>98%


Description

SP600125 is a potent, cell-permeable, selective and reversible inhibitor of c-Jun N-terminal kinase (JNK).

 

It inhibits in a dose-dependent manner the phosphorylation of JNK. JNK is a member of the mitogen-activated protein kinase (MAPK) family and plays an essential role in TLR mediated inflammatory responses.

 

Inhibition of JNK activity by SP600125 is usually associated with downregulation of Beclin-1 and reduced autophagy.

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