Anti-human LFA-1 (CD11a) antibody
Anti-human LFA-1 (CD11a) antibody
Clone: TS-1/22.1.1.13 Catalog#: A10011
Description: The TS-1/22.1.1.13 monoclonal antibody reacts with human LFA-1α (lymphocyte function-associated antigen 1 alpha) also known as integrin alpha L chain and CD11a. LFA-1α and CD18 combine to form LFA-1, a 180 kDa glycoprotein and a member of the integrin family. LFA-1 is expressed on the surface of all leukocytes including lymphocytes, monocytes, macrophages, and granulocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50), and also functions in lymphocyte costimulatory signaling.
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Isotype: |
Mouse IgG1 |
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Species reactivity: |
Human |
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Production: |
Tissue culture |
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Purification: |
Protein G |
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Recommended Isotype Control: |
Mouse IgG1 Isotype control |
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Applications: |
in vitro LFA-1 neutralization |
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Immunogen: |
Human LFA-1α |
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Storage: |
Store at +4°C short term (1-2 weeks). Store at -20°C long term. |
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Formulation: |
PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug. |
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Clonality: |
Monoclonal |