Broadly neutralizing antibodies against influenza A viruses, Fully human, CR8020

$1,999.00
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A90005
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Broadly neutralizing antibodies against influenza A viruses, Fully human, CR8020

Clone CR8020         Catalog#: A90005

 

Description:  CR8020is fully human neutralizing monoclonal antibody against on group 2 influenza A. CR8020 with broad neutralizing activity against most group 2 viruses, including H3N2 and H7N7, which cause severe human infection.  

 

 

Isotype:

IgG1

Species reactivity:

Human

Production:

Tissue culture

Purification:

Protein A

Applications:

Neutralization assay, In vivo protection etc.

Storage: 

Store at +4°C short term (1-2 weeks). Store at -20°C long term.

Formulation:

PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug.

Clonality:

Monoclonal

 

Reference:                           

  1. Ekiert DC, et al. (2011). A highly conserved neutralizing epitope on group 2 influenza A viruses. Science. 2011 Aug 12;333(6044):843-50.

 

  1. Tharakaraman K, et al. (2014). Broadly neutralizing influenza hemagglutinin stem-specific antibody CR8020 targets residues that are prone to escape due to host selection pressure.Cell Host Microbe. 2014 May 14;15(5):644-51.
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