Broadly neutralizing antibodies against influenza A and B viruses, Fully human, CR9114

Broadly neutralizing antibodies against influenza A and B viruses, Fully human, CR9114
Clone CR9114 Catalog#: A90001
Description: CR9114 is fully human neutralizing monoclonal antibody against all types of influenza A and inlfeunza B virusesCR9114 binds a conserved epitope in the HA stem and protects against lethal challenge with influenza A and B viruses. These antibodies may inform on development of monoclonal antibody-based treatments and a universal flu vaccine for all influenza A and B viruses.
Isotype: |
IgG1 |
Species reactivity: |
Human |
Production: |
Tissue culture |
Purification: |
Protein A |
Applications: |
Neutralization assay, In vivo protection etc. |
Storage: |
Store at +4°C short term (1-2 weeks). Store at -20°C long term. |
Formulation: |
PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug. |
Clonality: |
Monoclonal |
Reference:
- Dreyfus C, et al. (2012). Highly conserved protective epitopes on influenza B viruses.Science. 2012 Sep 14;337(6100):1343-8.