Anti AAV9 antibody, Clone HI17
Clone HI17 Catalog#: A20017
Description: Anti AAV9 antibody reacts with AAV-9 only. Adeno-associated virus (AAV) is a small virus which infects humans and some other primate species. AAV is not currently known to cause disease. The virus causes a very mild immune response, lending further support to its apparent lack of pathogenicity. Gene therapy vectors using AAV can infect both dividing and quiescent cells and persist in an extrachromosomal state without integrating into the genome of the host cell, although in the native virus some integration of virally carried genes into the host genome does occur.
|
Isotype: |
Mouse IgG1 |
|
Species reactivity: |
Mouse |
|
Production: |
Tissue culture |
|
Purification: |
Protein A/G |
|
Applications: |
ELISA, IF, etc. |
|
Immunogen: |
AAV9 virus |
|
Storage: |
Store at +4°C short term (1-2 weeks). Store at -20°C long term. |
|
Formulation: |
PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug. |
|
Clonality: |
Monoclonal |
References
1. Tseng YS, et al,(2016). Generation and characterization of anti-Adeno-associated virus serotype 8 (AAV8) and anti-AAV9 monoclonal antibodies. J Virol Methods. 2016 Oct;236:105-10.
2. Miyanohara A, et al, (2016). Potent spinal parenchymal AAV9-mediated gene delivery by subpial injection in adult rats and pigs. Mol Ther Methods Clin Dev. 2016 Jul 13;3:16046.
