African Swine Fever Virus (ASFV) p30 Monoclonal Antibody

$699.00
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A20067
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African Swine Fever Virus (ASFV) p30 Monoclonal Antibody

 Clone HI67          Catalog#: A20067

Description: Anti ASFV/p30 monoclonal antibody Specifically recognize ASFV p30 protein. African Swine Fever (ASF) is a contagious, septic viral disease of pigs, characterized by fever, toxicosis, haemorrhages and high mortality rate. The causative agent of the disease is ASFV, a large DNA virus from the Asfarviridae family. Domestic and wild pigs are all susceptible to ASFV regardless of the breed or age. The disease can occur in various forms, including fulminant, acute, subacute, chronic and inapparent. ASFV p30 protein is an early protein, a part of the inner membrane of the virus particle. it was determined that at the early stages of infection (3-­6 days post-­infection) by low, moderately and highly virulent strains of ASFV, the virus specific antibodies detectable in the blood sera are mainly specific to the structural virus protein p30. Thus, p30 is a valuable target for both serology and antigen detection in ASF.  

Isotype:

IgG2a

Species reactivity:

Mouse

Production:

Tissue culture

Purification:

Protein A/G

Applications:

ELISA, IFA, Bilateral flow, etc

Immunogen: 

sf9 expressed full length ASFV p30 protein (182 aminoacids)

Storage: 

Store at +4°C short term (1-2 weeks). Store at -20°C long term.

Formulation:

PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug.

Clonality:

Monoclonal

 

Reference:  1.  Kazakova AS, et al. (2017). Recombinant Protein p30 for Serological Diagnosis of African Swine Fever by ImmunoblottingAssay.TransboundEmergDis.Oct;;64(5):1479-­1492.

2. Pérez-­FilgueiraDM,etal.(2006).Optimizationandvalidationof recombinant serological tests for African Swine Fever diagnosis based ondetectionofthep30proteinproducedinTrichoplusianilarvae.JClin Microbiol.Sep;;44(9):3114-­21.

3. Cubillos C, et al. (2013). African swine fever virus serodiagnosis: a general review with a focus on the analyses of African serum samples. Virus Res.Apr;;173(1):159-­67.

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