Broadly neutralizing antibodies against influenza A viruses, Fully human, FI6, MEDI8852

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A90002
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Broadly neutralizing antibodies against influenza A viruses, Fully human, FI6, MEDI8852

Clone FI6         Catalog#: A90002

Description: FI6 (MEDI8852) is fully human neutralizing monoclonal antibody against influenza A. FI6 recognizes the hemagglutinin (HA) glycoprotein of all 16 subtypes and neutralized both group 1 and group 2influenza A viruses. FI6 may be used for passive protection and to inform vaccine design because of its broad specificity and neutralization potency..

  

Isotype:

IgG1

Species reactivity:

Human

Production:

Tissue culture

Purification:

Protein A

Applications:

Neutralization assay, In vivo protection etc.

Storage: 

Store at +4°C short term (1-2 weeks). Store at -20°C long term.

Formulation:

PBS, pH 7.4, Filter sterilized. Endotoxin level tests less than 0.06 EU/ug.

Clonality:

Monoclonal

 

Reference:                           

  1. Corti D, et al. (2011). A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins.Science. 2011 Aug 12;333(6044):850-6.
  2. Kallewaard NL, et al. (2016). Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes.Cell. 2016 Jul 28;166(3):596-608.
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